#70 Prioritizing drug target genes with Marie Sadler
In this episode, Marie Sadler talks about her recent Cell Genomics paper, Multi-layered genetic approaches to identify approved drug targets. Previou...
#69 Suffix arrays in optimal compressed space and δ-SA with Tomasz Kociumaka and Dominik Kempa
Today on the podcast we have Tomasz Kociumaka and Dominik Kempa, the authors of the preprint Collapsing the Hierarchy of Compressed Data Structures: S...
#68 Phylogenetic inference from raw reads and Read2Tree with David Dylus
In this episode, David Dylus talks about Read2Tree, a tool that builds alignment matrices and phylogenetic trees from raw sequencing reads. By leverag...
#67 AlphaFold and variant effect prediction with Amelie Stein
This is the third and final episode in the AlphaFold series, originally recorded on February 23, 2022, with Amelie Stein, now an associate professor a...
#66 AlphaFold and shape-mers with Janani Durairaj
This is the second episode in the AlphaFold series, originally recorded on February 14, 2022, with Janani Durairaj, a postdoctoral researcher at the U...
#65 AlphaFold and protein interactions with Pedro Beltrao
In this episode, originally recorded on February 9, 2022, Roman talks to Pedro Beltrao about AlphaFold, the software developed by DeepMind that predic...
#64 Enformer: predicting gene expression from sequence with Žiga Avsec
In this episode, Jacob Schreiber interviews Žiga Avsec about a recently released model, Enformer. Their discussion begins with life differences betwee...
#63 Bioinformatics Contest 2021 with Maksym Kovalchuk and James Matthew Holt
The Bioinformatics Contest is back this year, and we are back to discuss it! This year’s contest winners Maksym Kovalchuk (1st prize) and Matt Holt (...
#62 Steady states of metabolic networks and Dingo with Apostolos Chalkis
In this episode, Apostolos Chalkis presents sampling steady states of metabolic networks as an alternative to the widely used flux balance analysis (F...
#61 3D genome organization and GRiNCH with Da-Inn Erika Lee
In this episode, Jacob Schreiber interviews Da-Inn Erika Lee about data and computational methods for making sense of 3D genome structure. They begin...